Getting realtime results can result in a lower A1C on your next visit.
The A1C test is also called glycated hemoglobin, HbA1c, or glycosylated hemoglobin. A1C
provides an indication of your average blood glucose for the past 2-3 months.
Hemoglobin is part of the red blood cells and binds to glucose. The A1C complex is formed
when the glucose in the blood binds irreversibly (glycates) to hemoglobin. The higher the
glucose level in the blood, the more that binds to the hemoglobin. Therefore, A1C values are
proportional to the amount of glucose in the blood. The A1C result is in percentage (%) units
and reflects the percentage of the hemoglobin that is glycate1.
Hemoglobin remains glycated for the lifespan of the red blood cell, about 90-120 days.
Therefore, the A1C test reflects an average blood glucose control for the past 2-3 months.
Mean blood glucose of the 30 days prior to the A1C test contributes to 50% of the A1C value2
Fasting plasma glucose contributes more to A1C results in patients with poorly controlled diabetes.
In satisfactory to good control of diabetes, postprandial glucose is the predominant contributor.3,4
Testing Made Easy
- The ADA recommends that healthcare professionals use A1C point-of-care testing for timely decisions on therapy changes
- Giving diabetes patients on-the-spot feedback on their A1C number may result in a 1% point reduction in their A1C
- A 1% point reduction in A1C may lower the risk of complications by up to 40%*5
* in non-pregnant adults with type 2 diabetes.
1 American Diabetes Website, https://www.diabetes.org/type-1-diabetes/a1c-test.jsp.
2 Calisti L, Tognetti, S. "Measure of Glycosylated Hemoglobin", Acta Biomed, (2005); 76, suppl 3: pp. 59-62.
3 Woerle, HJ, Neumann, C, Zachau, S, Tenner S, Irsigler, A, Schirra, J, Gerich, JE, Goke, B. "Impact of Fasting and Postprandial Glycemia on Overall Glycemic Control in Type 2 Diabetes. Importance of Postprandial Glycemia to Achieve Target HbA1C Levels.", Diabetes Research and Clinical Practice, 77 (2007); pp 280-285.
4 Monnier, L, Colette C. "Contributions of Fasting and Postprandial Glucose To Hemoglobin A1C" Endocrine Practice Vol 12 (Suppl 1) Jan/Feb 2006; pp 42-46.
5 Stratton IM, Adler Al, Neil AW, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study, BMJ.2000;321:405-4